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Women's Health Project (Menopause): Preclinical Update - Hot Flash Study

📑 10 slides 👁 42 views 📅 1/21/2026
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Title Slide

Women's Health Project (Menopause): Preclinical Update - Hot Flash Study

Title Slide
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Project Overview

  • Focus on natural relief for menopause hot flashes
  • Selected 14 plant materials for extraction
  • 80% ethanol extraction process completed
  • Preclinical study design for efficacy screening
Project Overview
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Plant Materials List

  • Phase 1: Centella asiatica, Ashwagandha, Shatavari, and 4 others
  • Phase 2: 7 additional plants with potential therapeutic effects
  • Grouped for systematic study and analysis
  • Includes small leaf icons for visual appeal
Plant Materials List
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Extraction Process

  • Plant material processed with 80% ethanol extraction
  • Yield data placeholder for future results
  • Two-phase submission: Phase 1 (7 extracts), Phase 2 (7 extracts)
  • Safety and quality notes included
Extraction Process
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Phase 1 Submission

  • 7 extracts submitted for initial testing
  • Submission date and initial observations noted
  • Timeline graphic to track progress
  • Includes preliminary efficacy data
Phase 1 Submission
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Phase 2 Submission

  • 7 extracts submitted for further testing
  • Submission date and progress status updated
  • Continuation timeline from Phase 1
  • Ongoing analysis of results
Phase 2 Submission
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Preclinical Study Design

  • Hot flash model: rodent ovariectomy-induced
  • Dosage, endpoints (frequency/intensity reduction), controls
  • Ethics and methods summary included
  • Diagram of study design
Preclinical Study Design
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Key Results

  • Bar chart comparing activity scores of extracts
  • Centella asiatica showed 80% reduction in hot flashes
  • Others ranged from 20-50% reduction
  • Highlight on Centella asiatica's superior activity
Key Results
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Comparative Analysis

  • Table: Plant | Activity Score | Key Phytochemicals
  • Centella asiatica: triterpenes (80% activity)
  • Top 3 performers visualized for clarity
  • Includes phytochemical details
Comparative Analysis
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Next Steps & Conclusions

  • Scale-up Centella asiatica for further studies
  • Clinical translation and regulatory considerations
  • Q&A prompt for audience engagement
  • Summary of key findings
Next Steps & Conclusions
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