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Cushing Syndrome

📑 5 slides 👁 9 views 📅 2/26/2026
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What is Cushing Syndrome?

A hormonal disorder caused by prolonged exposure to high cortisol levels.

What is Cushing Syndrome?
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Symptoms of Cushing Syndrome

  • Weight gain, especially in the face (moon face) and upper back (buffalo hump).
  • Thin skin that bruises easily and slow-healing wounds.
  • Muscle weakness and fatigue due to protein breakdown.
Symptoms of Cushing Syndrome
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Causes and Risk Factors

  • Most common cause: prolonged use of corticosteroid medications.
  • Tumors in the pituitary or adrenal glands can overproduce cortisol.
  • Rarely caused by ectopic ACTH-producing tumors outside the pituitary.
Causes and Risk Factors
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Diagnosis and Tests

  • 24-hour urinary free cortisol test to measure cortisol levels.
  • Dexamethasone suppression test to check cortisol regulation.
  • Imaging tests like MRI or CT scans to locate tumors.
Diagnosis and Tests
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Treatment and Management

  • Reducing steroid use under medical supervision if drug-induced.
  • Surgical removal of tumors causing excess cortisol production.
  • Medications to control cortisol levels when surgery isn't an option.
Treatment and Management
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